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2648403-17-0

2648403-17-0 Structure

2648403-17-0 Structure
IdentificationBack Directory
[Name]

1,2,4-Triazine-3,5(2H,4H)-dione, 2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-6-(fluoromethyl)-
[CAS]

2648403-17-0
[Synonyms]

THR-β agonist 1
1,2,4-Triazine-3,5(2H,4H)-dione, 2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-6-(fluoromethyl)-
[Molecular Formula]

C17H14Cl2FN5O4
[MOL File]

2648403-17-0.mol
[Molecular Weight]

442.23
Chemical PropertiesBack Directory
[density ]

1?+-.0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

5.33±0.40(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

THR-β Agonist 1 is a potent and selective agonist of THRβ. Thyroid hormone receptor mediates the physiological activity of thyroid hormones which plays a key role in normal growth and development of the body and in maintaining metabolic balance. THR-β Agonist 1 has the potential for the research of thyroid hormone receptor-related diseases (extracted from patent WO2021104288A1, compound 2)[1].
[References]

[1] Hejun lv, et al. 1,2,4-triazine-3,5-dione compound and its preparation method and application. Patent WO2021104288A1.
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