ChemicalBook--->CAS DataBase List--->2648939-40-4

2648939-40-4

Request For Quotation
2648939-40-4 Structure

2648939-40-4 Structure
IdentificationBack Directory
[Name]

5,6-dichloro-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
[CAS]

2648939-40-4
[Synonyms]

Thalidomide-5,6-Cl
1H-Isoindole-1,3(2H)-dione, 5,6-dichloro-2-(2,6-dioxo-3-piperidinyl)-
5,6-dichloro-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
[Molecular Formula]

C13H8Cl2N2O4
[MDL Number]

MFCD34167838
[MOL File]

2648939-40-4.mol
[Molecular Weight]

327.12
Chemical PropertiesBack Directory
[Boiling point ]

590.1±50.0 °C(Predicted)
[density ]

1.672±0.06 g/cm3(Predicted)
[pka]

10.52±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Thalidomide-5,6-Cl is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-Cl can be connected to the ligand for protein by a linker to form PROTACs.
[IC 50]

Cereblon
[References]

[1] Zhang NN, et, al. A Thermostable mRNA Vaccine against COVID-19. Cell. 2020 Sep 3;182(5):1271-1283.e16. DOI:10.1016/j.cell.2020.07.024
2648939-40-4 suppliers list
Company Name: Shanghai Easy CDMO Co.,Ltd  
Tel: 021-61734564 13854185395;
Website:
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology  
Tel: 18143011203
Website: http://www.chemextension.com/
Company Name: Henan Mengtai Pharmaceutical Technology Co., Ltd  
Tel: 176345344 7 17634854698
Website: https://www.henanmengtai.com
Tags:2648939-40-4 Related Product Information
2097509-40-3 2446382-02-9 2162120-73-0 2357110-84-8 2639395-34-7 2169266-69-5 1957235-91-4 2169266-64-0 2245697-88-3 2093536-13-9 2225148-52-5 2087490-48-8 1799711-29-7 2227423-38-1