| Identification | Back Directory | [Name]
Coronalolide methyl ester | [CAS]
268214-50-2 | [Synonyms]
NSC 680073
Coronalolide methyl ester
1H-Cyclopenta[7,8]cyclopropa[4,4a]naphtho[2,3-b]furan-10b(2H)-propanoic acid, 4-[(1R,4E)-1,5-dimethyl-6-oxo-4-hexen-1-yl]dodecahydro-3a,6a-dimethyl-10-methylene-9-oxo-, methyl ester, (1aS,3aR,4R,6aS,6bS,7aR,10aR,10bR)- | [Molecular Formula]
C31H44O5 | [MDL Number]
MFCD20260603 | [MOL File]
268214-50-2.mol | [Molecular Weight]
496.68 |
| Hazard Information | Back Directory | [Uses]
Coronalolide methyl ester (NSC 680073) is a natural triterpene with anticancer effects. Coronalolide methyl ester shows moderately cytotoxic to KATO-3, SW-620, and Hep-G2 cells., with IC50 values of 8.64 μg/mL, 6.19 μg/mL, and 6.8 μg/mL, respectively[1]. | [References]
[1] Thanesuan Nuanyai, et al. Cytotoxic 3,4-seco-cycloartane triterpenes from Gardenia sootepensis. J Nat Prod. 2009 Jun;72(6):1161-4. DOI:10.1021/np900156k |
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