| Identification | Back Directory | [Name]
OXYSOPHOCARPINE | [CAS]
26904-64-3 | [Synonyms]
ophocarpidine
Sophocarpidin
OXYSOPHOCARPINE
N-OXYSOPHOCARPINE
Sophocarpine N-oxide
OXYSOPHOCARPINE USP/EP/BP
Oxysophocarpine 26904-64-3
1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, 2,3,6,7,7a,8,13,13a,13b,13c-decahydro-, 4-oxide, (4R,7aS,13aR,13bR,13cS)- | [Molecular Formula]
C15H22N2O2 | [MDL Number]
MFCD04040982 | [MOL File]
26904-64-3.mol | [Molecular Weight]
262.351 |
| Chemical Properties | Back Directory | [Melting point ]
73-76 °C | [solubility ]
Soluble in chloroform and water | [form ]
powder | [pka]
4.92±0.20(Predicted) | [color ]
White-pale yellow | [InChI]
InChI=1S/C15H22N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h1,7,11-13,15H,2-6,8-10H2/t11-,12+,13+,15?,17+/m0/s1 | [InChIKey]
QMGGMESMCJCABO-RDVIFRKPSA-N | [SMILES]
[N@@+]12([O-])CCC[C@]3([H])C1[C@@]([H])([C@@]1([H])CC=CC(=O)N1C3)CCC2 |
| Hazard Information | Back Directory | [Chemical Properties]
It is soluble in water, methanol, ethanol, chloroform, and benzene, but poorly soluble in ether. It is derived from the plant Sophra flavescens Ait. | [Uses]
Oxysophocarpine is an alkaloid extract from Siphocampylus verticillatus it maintains anti-nociceptive effects through systemic and intracerebroventricular administration in rodents. Derivative of Sophocarpine (S676825), an antiviral agent. | [Synthesis]
Extraction from wolfsbane flowers:
1) Pretreatment: Soaking with a mushroom filtrate.
2) Extraction: Sequential extraction with organic solvents and dilute acetic acid solution. The extracts are combined.
3) Water precipitation: The extract is di |
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