| Identification | Back Directory | [Name]
oxysophoridine | [CAS]
54809-74-4 | [Synonyms]
Ordinariness
oxysophoridine
N-Oxysophoridine
Sophoridine oxide
Sophoridine N-oxide
(-)-Sophoridine N-oxide
Matridin-15-one, 1-oxide,(5β)-
Sophoridine N-oxide/oxysophoridine
1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one,dodecahydro-, 4-oxide, (7aR,13aR,13bR,13cS)- | [Molecular Formula]
C15H24N2O2 | [MDL Number]
MFCD31664884 | [MOL File]
54809-74-4.mol | [Molecular Weight]
264.36 |
| Chemical Properties | Back Directory | [Melting point ]
162-4°C | [storage temp. ]
2-8°C | [solubility ]
|DMSO : 25 mg/mL (94.57 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [pka]
4.87±0.20(Predicted) | [color ]
White to off-white | [Water Solubility ]
Water : 125 mg/mL (472.84 mM; Need ultrasonic) | [InChI]
InChI=1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12-,13-,15?,17?/m1/s1 | [InChIKey]
XVPBINOPNYFXID-CSTKHBIYSA-N | [SMILES]
[N+]12([O-])CCC[C@@]3([H])C1[C@@]([H])([C@@]1([H])CCCC(=O)N1C3)CCC2 |
| Hazard Information | Back Directory | [Description]
This alkaloid has been described by Russian workers who have isolated it from
Sophora alopecuroides L. It yields colourless needles from Me2CO and a specific
rotation of [α]D- 50.6° (c 0.555, EtOH). Acetylation furnishes the O-acetate
withm.p.14S-7°C. | [Chemical Properties]
It is soluble in organic solvents such as methanol, ethanol, and DMSO, and is derived from Sophora alopecuroides and Acacia. | [Uses]
Oxysophoridine (Sophoridine N-oxide) is a bioactive alkaloid extracted from the Sophora alopecuroides Linn. Oxysophoridine (Sophoridine N-oxide) shows anti inflammatory, anti oxidative stress and anti apoptosis effects[1][2]. | [Definition]
ChEBI: Ammothamnine is an alkaloid and a tertiary amine oxide. | [References]
Monakhova et at., Khim. Prir. Soedin., 9,59 (1973) |
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