| Identification | Back Directory | [Name]
POLYINOSINIC ACID (5') POTASSIUM SALT | [CAS]
26936-41-4 | [Synonyms]
Poly I-K
POLY RL POTASSIUM SALT
POLY[I] POTASSIUM SALT
Potassium polyinosinate
Polyinosinic acid potassium
POLYINOSINIC ACID POTASSIUM SALT
polyinosinic acid (5') potassium
POLYINOSINIC ACID TRIPOTASSIUM SALT
POLYINOSINIC ACID (5') POTASSIUM SALT
Polyinosinic acid potassium salt (PI-K)
POLYINOSIC ACID, POTASSIUM SALT extrapure
Polyinosinic acid potassium salt Homopolymer
Polyinosinic Acid Potassium Salt (POLY I Potassium) extrapure
Potassium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl hydrogen phosphate | [Molecular Formula]
C10H12KN4O8P | [MDL Number]
MFCD00131982 | [MOL File]
26936-41-4.mol | [Molecular Weight]
386.296 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [solubility ]
water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow | [form ]
lyophilized powder | [biological source]
synthetic (organic) | [Water Solubility ]
water: 4.80-5.20mg/mL, clear to hazy, colorless to faintly yellow |
| Hazard Information | Back Directory | [Uses]
POLYINOSINIC ACID (5') POTASSIUM SALT is a homopolymer of inosine that may be used with polycytidylic acid (poly(C)) to form the double-stranded homopolymer (Poly(I) • Poly(C)). TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. POLYINOSINIC ACID (5') POTASSIUM SALT is a used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand. |
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