| Identification | Back Directory | [Name]
1-METHYL-DL-TRYPTOPHAN | [CAS]
26988-72-7 | [Synonyms]
Me-L-Trp
(Rac)-Indoximod
Tryptophan, 1-methyl-
1-METHYL-DL-TRYPTOPHAN
N-Methyl-DL-tryptophan
1-Methyl-DL-tryptophan 97%
1-METHYL-DL-TRYPTOPHAN USP/EP/BP
(2R)-2-ammonio-3-(1-methyl-3-indolyl)propanoate
2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
rac-(R*)-2-(1-Methyl-1H-indole-3-ylmethyl)glycine | [EINECS(EC#)]
248-157-6 | [Molecular Formula]
C12H14N2O2 | [MDL Number]
MFCD00005803 | [MOL File]
26988-72-7.mol | [Molecular Weight]
218.25 |
| Chemical Properties | Back Directory | [Melting point ]
250 °C (dec.)(lit.)
| [Boiling point ]
429.3±35.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [form ]
Solid | [pka]
2.26±0.10(Predicted) | [color ]
White to off-white | [InChI]
1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16) | [InChIKey]
ZADWXFSZEAPBJS-UHFFFAOYSA-N | [SMILES]
Cn1cc(CC(N)C(O)=O)c2ccccc12 |
| Hazard Information | Back Directory | [Uses]
1-Methyl-DL-tryptophan, a competitive inhibitor of indoleamine 2,3 dioxygenase-1 (IDO1), has been used to study inflammation-induced depression in mice and syncytial virus induced bronchiolitis. | [Uses]
1-Methyltryptophan is a reagent that is used in the rational design of a minimalist multifunctional photo-immunotherapy nanoplatform toward boosting immunotherapy capability. | [Definition]
ChEBI: A tryptophan derivative that is tryptophan carrying a single methyl substituent at position 1 on the indole. | [IC 50]
IDO | [storage]
4°C, protect from light |
|
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Sigma-Aldrich
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