| Identification | Back Directory | [Name]
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) | [CAS]
27244-64-0 | [Synonyms]
Topa
6-oh-dopa
Topaquinone
l-hydroxydopa
Hydroxy-L-dopa
l-6-hydroxydopa
6-Hydroxy-L-DOPA
6-Hydroxydopa, L-
2-Hydroxy Levodopa
Levodopa EP Impurity A
2,5-dihydroxy-l-tyrosine
L-Tyrosine, 2,5-dihydroxy-
Levadopa Related Compound A
Levodopa Related CoMpound A
l-2,4,5-trihydroxyphenylalanine
2,4,5-Trihydroxy-L-phenylalanine
4,5-trihydroxyphenyl)-3-(l-alanin
3-(3,4,6-Tirhydroxyphenyl)-alanine
3-(3,4,6-Trihydroxyphenyl)-L-alanine
3-(2,4,5-Trihydroxyphenyl)-L-alanine
Levodopa Impurity 1 (Levodopa EP Impurity A)
6-Hydroxy L-DOPA (Levadopa Related Compound A)
6-Hydroxy-L-DOPA (Levodopa Related CoMpound A)
(S)-α-Amino-3,4,6-trihydroxybenzenepropanoic acid
(S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid
(2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
Levodopa EP Impurity A/ Levodopa Related Compound A (2-Hydroxy Levodopa)
Levodopa Related Compound A ((3-(2,4,5-Trihydroxyphenyl)-L-alanine) or (3-(3,4,6-Trihydroxyphenyl)a (1361010) | [Molecular Formula]
C9H11NO5 | [MOL File]
27244-64-0.mol | [Molecular Weight]
213.19 |
| Chemical Properties | Back Directory | [Melting point ]
>190°C (dec.) | [Boiling point ]
515.2±38.0 °C(Predicted) | [density ]
1.606±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Aqueous Acid (Slightly, Sonicated), Water (Slightly, Heated, Sonicated) | [form ]
neat | [pka]
2.34±0.25(Predicted) | [color ]
Brown to Black | [Stability:]
Air Sensitive, Hygroscopic |
| Hazard Information | Back Directory | [Uses]
6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase. | [Uses]
6-Hydroxy-L-DOPA is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase. | [Definition]
ChEBI: An L-alpha-amino acid that is L-dopa carrying an additional hydroxy substituent at position 6. |
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