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2736508-65-7

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2736508-65-7 Structure

2736508-65-7 Structure
IdentificationBack Directory
[Name]

BGB-116673
[CAS]

2736508-65-7
[Synonyms]

BGB-116673
[Molecular Formula]

C47H54N12O4
[MOL File]

2736508-65-7.mol
[Molecular Weight]

851.01
Chemical PropertiesBack Directory
[density ]

1.284±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[pka]

7.48±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

PROTAC BTK Degrader-12 (EXAMPLE 19) is a PROTAC-based BTK degrader (Pink & black: BTK ligand & linker (HY-170414); Black: linker (HY-30105); Blue: VHL ligand ( HY-W245311))[1].
[References]

[1] Hexiang Wang, et al. Degradation of bruton's tyrosine kinase (btk) by conjugation of btk inhibitors with e3 ligase ligand and methods of use. Patent WO2021219070A1.
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