| Identification | More | [Name]
6-OXO-1,4,5,6-TETRAHYDROPYRIDAZIN-3-CARBOXYLIC ACID | [CAS]
27372-38-9 | [Synonyms]
6-OXO-1,4,5,6-TETRAHYDROPYRIDAZIN-3-CARBOXYLIC ACID
6-OXO-1,4,5,6-TETRAHYDROPYRIDAZINE-3-CARBOXYLIC ACID
6-OXO-4,5-DIHYDRO-PYRIDAZINE-3-CARBOXYLIC ACID
AKOS BBS-00006915
OTAVA-BB BB7020410149
1,4,5,6-TETRAHYDRO-6-OXOPYRIDAZINE-3-CARBOXYLIC ACID, 97% | [Molecular Formula]
C5H6N2O3 | [MDL Number]
MFCD00052030 | [Molecular Weight]
142.11 | [MOL File]
27372-38-9.mol |
| Questions And Answer | Back Directory | [Synthesis]
2.2 g of α-ketoglutaric acid was added to a single-necked flask containing 5 mL of water. 9 mL of hydrazine hydrate was slowly added dropwise (3-4 min) with stirring at room temperature. The solution gradually turned pale yellow. After stirring for 30 min, the solution was placed in a refrigerator. After 3 h, it was filtered to obtain 2.07 g of a white powder, with a yield of 98.1%. mp 265 ℃. This powder was used directly in the next reaction. | [Uses]
6-Chlorpyridazine-3-carboxylic acid methyl ester has become an important drug and intermediate for anti-tumor, antibacterial and agricultural pesticide applications due to its chemical and biochemical properties. It is also an important intermediate for the preparation of stearoyl-CoA desaturase to treat obesity. |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [HazardClass ]
IRRITANT |
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| Company Name: |
J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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400-0056266 |
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www.energy-chemical.com |
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