| Identification | Back Directory | [Name]
5-Pyrimidinecarboxamide, 4-[[2-(hydroxymethyl)phenyl]amino]-2-[(1,2,3,4-tetrahydro-6-methoxy-2-methyl-7-isoquinolinyl)amino]- | [CAS]
2739844-28-9 | [Synonyms]
HPK1-IN-4
5-Pyrimidinecarboxamide, 4-[[2-(hydroxymethyl)phenyl]amino]-2-[(1,2,3,4-tetrahydro-6-methoxy-2-methyl-7-isoquinolinyl)amino]- | [Molecular Formula]
C23H26N6O3 | [MOL File]
2739844-28-9.mol | [Molecular Weight]
434.49 |
| Chemical Properties | Back Directory | [Boiling point ]
694.9±65.0 °C(Predicted) | [density ]
1.347±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
13.93±0.50(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
HPK1-IN-4 (comp 22) is a HPK1 (MAPK41) inhibitor (IC50 of 0.061 nM) as preclinical immunoresearch tool compound[1]. | [Biological Activity]
HPK1-IN-4 (comp 22) is a HPK1 (MAPK41) inhibitor (IC50 of 0.061 nM) as preclinical immunotherapy tool compound[1]. | [storage]
Store at -20°C | [References]
[1]. Brandon A Vara, et al. Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds. ACS Med Chem Lett. 2021 Mar 19;12(4):653-661. |
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| Company Name: |
Bide Pharmatech Ltd.
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| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
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