| Identification | Back Directory | [Name]
3H-1,2,4-Triazol-3-one, 2-[4-[2-(2-chloro-6-fluorophenyl)-1-fluoroethenyl]-2-fluoro-5-[(1S)-2,2,2-trifluoro-1-methylethoxy]phenyl]-4-ethyl-2,4-dihydro-5-(hydroxymethyl)- | [CAS]
2742675-85-8 | [Synonyms]
DHODH-IN-19
3H-1,2,4-Triazol-3-one, 2-[4-[2-(2-chloro-6-fluorophenyl)-1-fluoroethenyl]-2-fluoro-5-[(1S)-2,2,2-trifluoro-1-methylethoxy]phenyl]-4-ethyl-2,4-dihydro-5-(hydroxymethyl)- | [Molecular Formula]
C22H18ClF6N3O3 | [MOL File]
2742675-85-8.mol | [Molecular Weight]
521.84 |
| Hazard Information | Back Directory | [Uses]
DHODH-IN-19 is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-19 inhibits tumor growth. DHODH-IN-19 has the potential for the research of cancer and inflammation disease (extracted from patent WO2021238881A1, compound 1)[1]. | [References]
[1] Shuhui Chen, et al. Triazolones. Patent WO2021238881A1. |
|
|