| Identification | Back Directory | [Name]
cholest-5-ene-3,24(R)-diol | [CAS]
27460-26-0 | [Synonyms]
24-Epicerebrosterol
cholest-5-ene-3,24(R)-diol
(24R)-24-hydroxycholesterol
Cholest-5-ene-3,24-diol, (3β,24R)-
CHOLEST-5-ENE-3,24(R)-DIOL;24(R)-HYDROXYCHOLESTEROL | [Molecular Formula]
C27H46O2 | [MOL File]
27460-26-0.mol | [Molecular Weight]
402.65 |
| Chemical Properties | Back Directory | [Melting point ]
177-180 °C(Solv: methanol (67-56-1)) | [Boiling point ]
513.1±23.0 °C(Predicted) | [density ]
1.03±0.1 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Solid | [pka]
15.03±0.70(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
24-Epicerebrosterol is aan oxysterol regulator. | [Definition]
ChEBI: (24R)-24-hydroxycholesterol is a 24-hydroxycholesterol that has R configuration at position 24. It has a role as a nuclear receptor modulator and a mouse metabolite. | [Biological Activity]
24(S)-hydroxycholesterol is preferred over 24(R)-hydroxycholesterol by human 7α-hydroxylase. Howeverthe porcine enzyme is active towards both isomers. 24-hydroxycholesterol (24-OH) favors sirtuin 1 expression and reduces the tau protein phosphorylation. | [storage]
Store at -20°C |
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