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2765539-92-0

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2765539-92-0 Structure

2765539-92-0 Structure
IdentificationBack Directory
[Name]

(αS)-2-[1-[(1R)-1-(2,6-Dichloro-3-cyclopropylphenyl)ethyl]-1H-imidazo[4,5-c]pyridin-6-yl]-α-methylbenzeneacetic acid
[CAS]

2765539-92-0
[Synonyms]

(αS)-2-[1-[(1R)-1-(2,6-Dichloro-3-cyclopropylphenyl)ethyl]-1H-imidazo[4,5-c]pyridin-6-yl]-α-methylbenzeneacetic acid
[Molecular Formula]

C26H23Cl2N3O2
[MOL File]

2765539-92-0.mol
[Molecular Weight]

480.39
Chemical PropertiesBack Directory
[Boiling point ]

665.3±65.0 °C(Predicted)
[density ]

1.41±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[pka]

4.16±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

(S,R)-LSN3318839 is the stereoisomer of LSN3318839 (HY-142162). LSN3318839 is an orally active positive modulator of the glucagon-like peptide-1 receptor (GLP-1R). LSN3318839 can increase the secretion of insulin and has the effect of lowering blood sugar[1].
[References]

[1] Willard FS, et al., Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide-1 Receptor. J Med Chem. 2021 Mar 25;64(6):3439-3448. DOI:10.1021/acs.jmedchem.1c00029
Spectrum DetailBack Directory
[Spectrum Detail]

(αS)-2-[1-[(1R)-1-(2,6-Dichloro-3-cyclopropylphenyl)ethyl]-1H-imidazo[4,5-c]pyridin-6-yl]-α-methylbenzeneacetic acid(2765539-92-0)1HNMR
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