| Identification | Back Directory | [Name]
DIMETHISOQUIN HYDROCHLORIDE (2 G) | [CAS]
2773-92-4 | [Synonyms]
quotane
QuinisocaineHCl
quinisocainehydrochloride
chinisocainehydrochloride
dimethisoquinhydrochloride
Dimethisoquin hydrochloride (2 g)
Dimethisoquin Hydrochloride (1208001)
3-butyl-1-(2-(dimethylamino)ethoxy)isoquinolinehydrochloride
3-butyl-1-(2-(dimethylamino)ethoxy)-isoquinolinhydrochloride
2-[(3-butyl-1-isoquinolyl)oxy]ethyl(dimethyl)ammonium chloride
1-(beta-dimethylaminoethoxy)-3-n-butylisoquinolinehydrochloride
1-(beta-dimethylaminoethoxy)-3-n-butylisoquinolinemonohydrochloride
2-((3-butyl-1-isoquinolinyl)oxy)-n,n-dimethyl-ethanaminmonohydrochloride | [EINECS(EC#)]
220-468-1 | [Molecular Formula]
C17H25ClN2O | [MDL Number]
MFCD00050649 | [MOL File]
2773-92-4.mol | [Molecular Weight]
308.846 |
| Chemical Properties | Back Directory | [Definition]
An ointment and lotion containing
dimethisoquin hydrochloride. | [Melting point ]
145.5°C | [density ]
1.0887 (rough estimate) | [refractive index ]
1.5800 (estimate) | [storage temp. ]
Hygroscopic, Refrigerator, under inert atmosphere | [solubility ]
DMSO (Slightly, Heated), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Originator]
Quotane,SKF,US,1951 | [Uses]
Dimethisoquin Hydrochloride is a local anesthetic. | [Manufacturing Process]
A mixture of 10.0 grams of β-dimethylaminoethanol and 1.9 grams of sodium
in 90 cc of dry xylene was heated at 95°C for 5 hours. To the resulting
solution was added at 30°C, 18 grams of 3-butyl-1-chloroisoquinoline. The
solution, which turned very dark, was heated at 100°-125°C for 3.5 hours.
The mixture was extracted with two 100 cc portions of 2N hydrochloric acid
solution. The acid solution was made strongly alkaline with 40% potassium
hydroxide solution and the oil which separated was taken into ether. The ether
solution was washed with two 100 cc portions of water saturated with sodium
chloride, and then dried over anhydrous sodium sulfate for 3 hours. The
sodium sulfate was removed by filtration and the ether by distillation.
Distillation of the residual oil gave a colorless liquid, BP 155°-157°C/3mm. | [Therapeutic Function]
Local anesthetic |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|