| Identification | Back Directory | [Name]
INDEX NAME NOT YET ASSIGNED | [CAS]
2828432-41-1 | [Synonyms]
602627-1
(S)-6-Amino-N-(2-(((2S,3S)-1-(((S)-1-(((S)-1-amino-3-hydroxy-1-oxopropan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-3-methyl-1-oxopentan-2-yl)amino)-2-oxoethyl)-2-((S)-2-amino-3-methylbutanamido)hexanamide 2,2,2-trifluoroacetate | [Molecular Formula]
C30H55F3N8O9 | [MOL File]
2828432-41-1.mol | [Molecular Weight]
728.8 |
| Hazard Information | Back Directory | [Uses]
VKGILS-NH2 TFA is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 TFA has no effect on DNA synthesis in cells[1][2]. | [IC 50]
PAR2 | [References]
[1] M Tognetto, et al. Evidence That PAR-1 and PAR-2 Mediate Prostanoid-Dependent Contraction in Isolated Guinea-Pig Gallbladder. Br J Pharmacol. 2000 Oct;131(4):689-94. DOI:10.1038/sj.bjp.0703618
[2] David A Vesey, et al. Proinflammatory and Proliferative Responses of Human Proximal Tubule Cells to PAR-2 Activation. Am J Physiol Renal Physiol. 2007 Nov;293(5):F1441-9. DOI:10.1152/ajprenal.00088.2007 |
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Biorbyt Ltd.
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