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2866301-18-8

2866301-18-8 Structure

2866301-18-8 Structure
IdentificationBack Directory
[Name]

GGFG-amide-glycol-amide-Exatecan
[CAS]

2866301-18-8
[Synonyms]

GGFG-amide-glycol-amide-Exatecan
[Molecular Formula]

C43H47FN8O11
[MOL File]

2866301-18-8.mol
[Molecular Weight]

870.88
Chemical PropertiesBack Directory
[Boiling point ]

1334.9±65.0 °C(predicted)
[density ]

1.49±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

10.70±0.40(predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

GGFG-amide-glycol-amide-Exatecan (Intermediate 2) is an Exatecan (HY-13631) derivative and can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50]

Camptothecins
[References]

[1] Marija VRLJIC, et al. Exatecan derivatives and antibody-drug conjugates thereof. WO2022236136A1.
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