| Identification | Back Directory | [Name]
7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC ACID ETHYL ESTER | [CAS]
28705-46-6 | [Synonyms]
S0679
RARECHEM AB KA K019
ETHYL 7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLATE
Ethyl7-(Diethylamino)coumarin-3-carboxylate>
ethyl 7-(diethylamino)-2-oxochromene-3-carboxylate
ETHYL 7-DIETHYLAMINO-COUMARIN-3-CARBOXYLATE: 98.5%
7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC ACID ETHYL ESTER
7-Diethylamino-2-oxo-2H-1-benzopyran-3-carboxylic acid ethyl ester
2-Oxo-7-(diethylamino)-2H-1-benzopyran-3-carboxylic acid ethyl ester
7-(Diethylamino)-2-oxo-2H-1-benzopyran-3-carboxylic acid ethyl ester
2H-1-Benzopyran-3-carboxylicacid, 7-(diethylamino)-2-oxo-, ethyl ester | [Molecular Formula]
C16H19NO4 | [MDL Number]
MFCD00227484 | [MOL File]
28705-46-6.mol | [Molecular Weight]
289.33 |
| Chemical Properties | Back Directory | [Melting point ]
86 °C | [Boiling point ]
455.6±45.0 °C(Predicted) | [density ]
1.204 | [Fp ]
229.3℃ | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
2.83±0.20(Predicted) | [color ]
Light yellow to Amber to Dark green | [InChI]
InChI=1S/C16H19NO4/c1-4-17(5-2)12-8-7-11-9-13(15(18)20-6-3)16(19)21-14(11)10-12/h7-10H,4-6H2,1-3H3 | [InChIKey]
MSOLGAJLRIINNF-UHFFFAOYSA-N | [SMILES]
C1(=O)OC2=CC(N(CC)CC)=CC=C2C=C1C(OCC)=O | [EPA Substance Registry System]
2H-1-Benzopyran-3-carboxylic acid, 7-(diethylamino)-2-oxo-, ethyl ester (28705-46-6) |
| Hazard Information | Back Directory | [Uses]
Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate is a potent and selective inhibitor of hMAO-B with an IC50 of 45.52 μM[1]. | [References]
[1] Secci D, et al. Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives. Eur J Med Chem. 2011 Oct;46(10):4846-52. DOI:10.1016/j.ejmech.2011.07.017 |
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| Company Name: |
Energy Chemical
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| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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