| Identification | More | [Name]
5-METHOXY-2-METHYL-3-INDOLEACETIC ACID | [CAS]
2882-15-7 | [Synonyms]
(5-METHOXY-2-METHYL-1H-INDOL-3-YL)-ACETIC ACID
5-METHOXY-2-METHYL-3-INDOLEACETIC ACID
5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID
5-METHOXY-2-METHYL INDOLE ACETIC ACID
TIMTEC-BB SBB003362
VITAS-BB TBB000392
5-methoxy-2-methylindol-3-ylacetic acid
De(chlorobenzoyl)indomethacin.
5-methoxy-methylindoleacetic acid
5-METHOXY-2-METHYL-3-INDOLEACETIC ACID 98%
5-MeO,2-Me-IAA
(2-Methyl-5-methoxy-1H-indole-3-yl)acetic acid
5-Methoxy-2-methyl-1H-indole-3-acetic acid
N-Deschlorobenzoylindomethacin | [EINECS(EC#)]
220-734-7 | [Molecular Formula]
C12H13NO3 | [MDL Number]
MFCD00005618 | [Molecular Weight]
219.24 | [MOL File]
2882-15-7.mol |
| Chemical Properties | Back Directory | [Appearance]
slightly yellow fine crystalline powder | [Melting point ]
161-163 °C (lit.) | [Boiling point ]
360.05°C (rough estimate) | [density ]
1.1825 (rough estimate) | [refractive index ]
1.5270 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
methanol: soluble | [form ]
Crystalline Powder | [pka]
4.22±0.30(Predicted) | [color ]
Off-white to light yellow or light beige | [InChI]
1S/C12H13NO3/c1-7-9(6-12(14)15)10-5-8(16-2)3-4-11(10)13-7/h3-5,13H,6H2,1-2H3,(H,14,15) | [InChIKey]
TXWGINUZLBAKDF-UHFFFAOYSA-N | [SMILES]
COc1ccc2[nH]c(C)c(CC(O)=O)c2c1 | [CAS DataBase Reference]
2882-15-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29349990 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
slightly yellow fine crystalline powder | [Uses]
- Reactant for preparation of antimalarial agents
- Reactant for preparation of ndomethacin analogs as cyclooxygenase and lipoxygenase inhibitors with antiinflammatory activity
- Reactant for preparation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents
- Reactant for preparation of histone deacetylase inhibitors
- Reactant for preparation of 2,N6,5′-substituted adenosine derivatives as ligands for A2B adenosine receptor
- Reactant for preparation of prostaglandin D2 receptor antagonist
| [Uses]
5-Methoxy-2-methyl-3-indoleacetic acid was used for quantitative determination of indomethacin and its major impurities in suppository and capsule formulations by HPLC. 5-Methoxy-2-methyl-3-indoleacetic acid was used in a study to develop fast, sensitive and simultaneous determination of metabolites of serotonin using liquid chromatography with mass spectrometric detection. | [Uses]
A metabolite of Indomethacin. | [Definition]
ChEBI: N-Deschlorobenzoyl indomethacin is a member of indole-3-acetic acids. | [General Description]
5-Methoxy-2-methyl-3-indoleacetic acid is hydrolysis product of indomethacin. |
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