| Identification | Back Directory | [Name]
1,3-Benzodioxol-5-ol, 6-[4-morpholinyl[4-(trifluoromethyl)phenyl]methyl]- | [CAS]
289657-30-3 | [Synonyms]
RDR03785
6-(Morpholino(4-(trifluoromethyl)phenyl)methyl)benzo[d][1,3]dioxol-5-ol
6-{morpholin-4-yl[4-(trifluoromethyl)phenyl]methyl}-1,3-dioxaindan-5-ol
1,3-Benzodioxol-5-ol, 6-[4-morpholinyl[4-(trifluoromethyl)phenyl]methyl]- | [Molecular Formula]
C19H18F3NO4 | [MOL File]
289657-30-3.mol | [Molecular Weight]
381.35 |
| Chemical Properties | Back Directory | [Boiling point ]
468.7±45.0 °C(Predicted) | [density ]
1.392±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 50mg/mL, clear, colorless | [form ]
Solid | [pka]
9.68±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
RDR 03785 is a covalent MIF inhibitor with an IC50 of 0.36 μM[1]. | [References]
[1] Cisneros JA, et al. Irregularities in enzyme assays: The case of macrophage migration inhibitory factor. Bioorg Med Chem Lett. 2016 Jun 15;26(12):2764-2767. DOI:10.1016/j.bmcl.2016.04.074 |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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