| Chemical Properties | Back Directory | [Boiling point ]
703.1±60.0 °C(predicted) | [density ]
1.49±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
12.18±0.70(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Galectin-3 antagonist 1 (compound 15) is a potent and selective Galectin-3 (Gal-3) antagonist with Kd value of 5.3 μM. Meanwhile, Galectin-3 antagonist 1 binds to various Galectin with Kd values of 250 μM (Gal-4N), 18 μM (Gal-4C), 450 μM (Gal-8C), respectively[1]. | [IC 50]
Galectin-3 | [References]
[1] Bum-Erdene K, et al. Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J Med Chem. 2022 Apr 28;65(8):5975-5989. DOI:10.1021/acs.jmedchem.1c01296 |
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