| Chemical Properties | Back Directory | [Boiling point ]
953.5±65.0 °C(predicted) | [density ]
1.190±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
14.07±0.40(predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
(S,R,S)-AHPC-PEG5-Boc is a E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for Cdc20 degrader CP5V[1]. | [IC 50]
VHL | [References]
[1] Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2. DOI:10.1016/j.ebiom.2019.10.013 |
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