| Chemical Properties | Back Directory | [Boiling point ]
478.691±45.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.539±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
0.021±0.30(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
h-NTPDase-IN-4 (compound 4c) is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8). | [References]
[1] Zaman G, Ullah S, Uzair M, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165. |
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