| Identification | Back Directory | [Name]
Bentazepam | [CAS]
29462-18-8 | [Synonyms]
CI-718
QM-6008
Thiadipon
Tiadipone
Thiadipone
Bentazepam
Knoll brand of bentazepam
1,3,6,7,8,9-Hexahydro-5-phenyl-2H-[1]benzothieno[2,3-e]-1,4-diazepin-2-one
2H-[1]Benzothieno[2,3-e]-1,4-diazepin-2-one, 1,3,6,7,8,9-hexahydro-5-phenyl-
5-Phenyl-6,7,8,9-tetrahydro-1H-benzo[4,5]thieno[2,3-e][1,4]diazepin-2(3H)-one
Bentazepam 5-Phenyl-6,7,8,9-tetrahydro-1H-benzo[4,5]thieno[2,3-e][1,4]diazepin-2(3H)-one | [Molecular Formula]
C17H16N2OS | [MDL Number]
MFCD00868003 | [MOL File]
29462-18-8.mol | [Molecular Weight]
296.39 |
| Chemical Properties | Back Directory | [Melting point ]
249.5°C | [Boiling point ]
197.5°C (rough estimate) | [density ]
1.1654 (rough estimate) | [refractive index ]
1.7400 (estimate) | [solubility ]
DMF:15.0(Max Conc. mg/mL);50.61(Max Conc. mM)
DMSO:15.0(Max Conc. mg/mL);50.61(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.84(Max Conc. mM) | [form ]
A crystalline solid | [pka]
13.24±0.40(Predicted) | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Originator]
Bentazepam,Laboratorios Made S. A. | [Uses]
Sedative-hypnotic. | [Definition]
ChEBI: Bentazepam is an organosulfur heterocyclic compound and an organonitrogen heterocyclic compound. | [Manufacturing Process]
To a solution of 3.4 kg N-phthalimidoacetic acid in 20 L of methylene chloride
was added a solution of 2.8 kg of 1,1-carbonyl diimidazol in 20 L of methylene
chloride. The mixture was refluxed for 1 hour. After cooling to the obtained
solution was added a solution of 4.3 kg of 2-amino-3-benzoyl-4,5-
tetramethylene thiophene in 30 L of methylene chloride and the reaction
mixture was refluxed for 16 hours. After cooling the mixture was washed with
30 L of water, dried with sodium sulfate and filtered. After removing the
solvent was obtained the 2-(N-phthalimidoacetylamino)-3-benzoyl-4,5-
tetramethylene thiophene, yield 70%, melting point 230°C. | [Therapeutic Function]
Anticonvulsant, Tranquilizer | [Safety Profile]
Moderately toxic by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of SOx and NOx. |
|
| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
RongNa Biotechnology Co.,Ltd
|
| Telephone: |
+86-86-13583358881 +8618560316533 |
| Website: |
https://www.chemicalbook.com/manufacturer/zibo-rongna-chemical-technology-403/ |
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