| Identification | Back Directory | [Name]
Sulfamic acid, 2-chloro-4-[5-[[methyl(2-methylphenyl)amino]carbonyl]-2-furanyl]phenyl ester | [CAS]
2990549-73-8 | [Synonyms]
Sulfamic acid, 2-chloro-4-[5-[[methyl(2-methylphenyl)amino]carbonyl]-2-furanyl]phenyl ester | [Molecular Formula]
C19H17ClN2O5S | [MOL File]
2990549-73-8.mol | [Molecular Weight]
420.87 |
| Chemical Properties | Back Directory | [Boiling point ]
612.4±65.0 °C(predicted) | [density ]
1.424±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
7.76±0.70(predicted) |
| Hazard Information | Back Directory | [Uses]
Steroid sulfatase-IN-4 (Compound 16) is an irreversible steroid sulfatase (STS) inhibitor with an IC50 of 25 nM against human STS. Steroid sulfatase-IN-4 can be used for the research of endometriosis[1]. | [References]
[1] Mohamed A, et al. Dual Targeting of Steroid Sulfatase and 17β-Hydroxysteroid Dehydrogenase Type 1 by a Novel Drug-Prodrug Approach: A Potential Therapeutic Option for the Treatment of Endometriosis. J Med Chem. 2022 Aug 22. DOI:10.1021/acs.jmedchem.2c00589 |
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