| Chemical Properties | Back Directory | [Boiling point ]
464.3±45.0 °C(predicted) | [density ]
1.193±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
10.00±0.20(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
HA-CD44 interaction inhibitor 2 (compound 5) is an Hyaluronic acid (HA)-CD44 interaction inhibitor that effectively disrupts the integrity of cancer spheroids. HA-CD44 interaction inhibitor 2 also exhibits antiproliferative activity against cancer cells[1]. | [References]
[1] Espejo-Román JM, et al. N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect. Eur J Med Chem. 2023 Oct 5;258:115570. DOI:10.1016/j.ejmech.2023.115570 |
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