| Identification | Back Directory | [Name]
ROBININ | [CAS]
301-19-9 | [Synonyms]
ROBININ
Nsc9222
Aids082734
Aids-082734
Robinin >=90.0% (HPLC)
kaempferol-3-o-gal-rham-7-o-rham
KAEMPFEROL 3-ROBINOSIDE 7-RHAMNOSIDE
KAEMPFEROL 3-O-ROBINOSIDE 7-RHAMNOSIDE
KAEMPFEROL-3-O-ROBINOSIDE-7-O-RHAMNOSIDE
kaempferol-3-O-galactose-rhamnose-7-O-rhamnose
yranosyl)oxy)-7-((6-deoxy-alpha-l-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyph
4h-1-benzopyran-4-one,3-((6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-galactop
4',5-Dihydroxy-7-(α-L-rhamnopyranosyloxy)-3-[(6-O-α-L-rhamnopyranosyl-β-D-galactopyranosyl)oxy]flavone
2-(4-Hydroxyphenyl)-3-[6-O-(α-L-rhamnopyranosyl)-β-D-galactopyranosyloxy]-5-hydroxy-7-(α-L-rhamnopyranosyloxy)-4H-1-benzopyran-4-one
3-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-galactopyranosyl]oxy]-7-[(6-deoxy-α-L-mannopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 3-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-galactopyranosyl]oxy]-7-[(6-deoxy-α-L-mannopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-
3-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-galactopyranosyl]oxy]-7-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 3-((6-o-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-galactopyranosyl)oxy)-7-((6-deoxy-.alpha.-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl | [EINECS(EC#)]
206-113-3 | [Molecular Formula]
C33H40O19 | [MDL Number]
MFCD00016940 | [MOL File]
301-19-9.mol | [Molecular Weight]
740.66 |
| Chemical Properties | Back Directory | [Chemical Properties]
Robinin is a flavone belonging to the flavonol glycosides occurring in Robinia species, e. g., Robinia pseudoacacia (Fabaceae) and in Pueraria and Vigna species (Fabaceae). Robinin has been reported to have antibacterial activity. | [Melting point ]
194-195°C | [Boiling point ]
1064.4±65.0 °C(Predicted) | [density ]
1.74±0.1 g/cm3(Predicted) | [storage temp. ]
?20°C | [solubility ]
Soluble in hot water | [form ]
powder | [pka]
5.81±0.40(Predicted) | [color ]
light yellow crystal. hydrate: light yellow needles. | [Water Solubility ]
soluble in hot water. | [LogP]
0.890 (est) | [CAS DataBase Reference]
301-19-9 |
| Hazard Information | Back Directory | [Uses]
food and beverages | [Definition]
ChEBI:Robinin is a glycosyloxyflavone that is kaempherol substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-galactopyranosyl residue at position 3 and a 6-deoxy-alpha-L-mannopyranosyl residue at position 7 via a glycosidic linkage. It has a role as a plant metabolite. It is a glycosyloxyflavone and a dihydroxyflavone. It is functionally related to a kaempferol. | [in vivo]
The combination of Robinin and methotrexate (50 mg/kg and 0.3 mg/kg, Oral gavage, Twice a week) has anti-inflammatory and anti-arthritic action in adjuvant arthritis mice models[3].
Robinin (50 mg/kg, Oral gavage, 10 days) can modulate the cardioprotective effect of the TGF-β1 signaling pathway on Adriamycin-induced cardiotoxicity[4].
| Animal Model: | Adjuvant arthritis mice model[3] | | Dosage: | 50 mg/kg Robinin and 0.3 mg/kg MTX twice a week | | Administration: | Oral gavage (p.o.) | | Result: | Had anti-inflammatory and anti-arthritic action. |
| Animal Model: | Sprague Dawley rats model[4] | | Dosage: | 50 mg/kg Robinin for 10 days | | Administration: | Oral gavage (p.o.) | | Result: | Reduced the cardiotoxic effects of Doxorubicin-induced |
| [IC 50]
TLR2; TLR4 | [storage]
4°C, protect from light |
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| Company Name: |
SiChuan HHTC Biological Technology Co., LTD Gold
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15982498737 18380486776 |
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