| Chemical Properties | Back Directory | [Boiling point ]
552.6±35.0 °C(predicted) | [density ]
1.077±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
15.30±0.46(predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
N-Boc-dolaproine-amide-Me-Phe is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity[1]. | [References]
[1] Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44(5): 937-940. |
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