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3026596-72-2

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3026596-72-2 Structure

3026596-72-2 Structure

Identification	Back Directory
[Name] N-Boc-dolaproine-amide-Me-Phe
[CAS] 3026596-72-2
[Synonyms] N-Boc-dolaproine-amide-Me-Phe
[Molecular Formula] C23H36N2O4
[MOL File] 3026596-72-2.mol
[Molecular Weight] 404.54

Chemical Properties	Back Directory
[Boiling point ] 552.6±35.0 °C(predicted)
[density ] 1.077±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ] Solid
[pka] 15.30±0.46(predicted)
[color ] Light yellow to yellow

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[Uses] N-Boc-dolaproine-amide-Me-Phe is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity[1].
[References] [1] Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44(5): 937-940.

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