| Chemical Properties | Back Directory | [Boiling point ]
1263.5±65.0 °C(predicted) | [density ]
1.28±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
13.93±0.20(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
CST626 (Compound 9) is a pan-IAP degrader PROTAC. CST626 degrades XIAP, cIAP1 and cIAP2 with DC50s of 0.7, 2.4, and 6.2 nM in MM.1S cells, respectively[1]. | [References]
[1] Ng YLD, et al. Heterobifunctional Ligase Recruiters Enable pan-Degradation of Inhibitor of Apoptosis Proteins. J Med Chem. 2023 Apr 13;66(7):4703-4733. DOI:10.1021/acs.jmedchem.2c01817 |
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| Company Name: |
R&D Systems, Inc
|
| Tel: |
18003437475 18003437475 |
| Website: |
www.rndsystems.com |
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