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3060-50-2

3060-50-2 Structure

3060-50-2 Structure
IdentificationMore
[Name]

2,2-DIPHENYLGLYCINE
[CAS]

3060-50-2
[Synonyms]

2,2-DIPHENYLGLYCINE
A,A-DIPHENYLGLYCINE
ALPHA,ALPHA-DIPHENYLGLYCINE
AMINODIPHENYLACETIC ACID
DIPHENYLGLYCIN
LABOTEST-BB LT00159592
2,2-diphenyl-glycin
alpha-amino-alpha-phenylbenzeneaceticacid
alpha-aminodiphenylaceticacid
alpa,alpha-Diphenylglycine
[EINECS(EC#)]

221-299-6
[Molecular Formula]

C14H13NO2
[MDL Number]

MFCD00008048
[Molecular Weight]

227.26
[MOL File]

3060-50-2.mol
Chemical PropertiesBack Directory
[Appearance]

white powder
[Melting point ]

245-247 °C (dec.) (lit.)
[Boiling point ]

368.97°C (rough estimate)
[density ]

1.231±0.06 g/cm3 (20 ºC 760 Torr)
[refractive index ]

1.5780 (estimate)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

DMSO (Slightly, Heated), Methanol (Slightly, Heated)
[form ]

Powder
[pka]

1.38±0.10(Predicted)
[color ]

White
[Water Solubility ]

It is sparingly soluble in water.
[Stability:]

Hygroscopic
[Major Application]

peptide synthesis
[InChI]

InChI=1S/C14H13NO2/c15-14(13(16)17,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,15H2,(H,16,17)
[InChIKey]

YBONNYNNFBAKLI-UHFFFAOYSA-N
[SMILES]

C(N)(C(=O)O)(C1C=CC=CC=1)C1C=CC=CC=1
[CAS DataBase Reference]

3060-50-2(CAS DataBase Reference)
Safety DataBack Directory
[Safety Statements ]

S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[RTECS ]

MC0176000
[HS Code ]

29224999
[Storage Class]

11 - Combustible Solids
Questions and Answers (Q&A)Back Directory
[Description]

2, 2-Diphenylglycine is a highly similar analogue and the simplest aromatic peptide. It can be used as a synthesis reagent for amination reactions. It is a useful intermediate in pharmaceutical and in organic synthesis. Its derivatives have been also be shown to exhibit anticonvulsants activity and can be used for the treatment of pain.
[References]

And, Meital Reches, and E. Gazit. "Formation of Closed-Cage Nanostructures by Self-Assembly of Aromatic Dipeptides." Nano Letters 4.4(2006):581-585.
https://www.alfa.com/en/catalog/B22650/
Harris, Robert H. "New uses for amino acid anticonvulsants for treatment of pain." EP, WO/2002/015922. 2002.
Hazard InformationBack Directory
[Chemical Properties]

white powder
[Uses]

2,2-Diphenylglycine is used as a synthesis reagent for amination reactions. It acts as an intermediate in pharmaceutical and in organic synthesis.
[reaction suitability]

reaction type: solution phase peptide synthesis
Spectrum DetailBack Directory
[Spectrum Detail]

2,2-Diphenylglycine(3060-50-2)MS
2,2-Diphenylglycine(3060-50-2)1HNMR
2,2-Diphenylglycine(3060-50-2)IR1
2,2-Diphenylglycine(3060-50-2)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

alpha,alpha-Diphenylglycine, 98%(3060-50-2)
[Alfa Aesar]

2,2-Diphenylglycine, 98%(3060-50-2)
[Sigma Aldrich]

3060-50-2(sigmaaldrich)
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