| Identification | Back Directory | [Name]
N-[2-[4-[[[2-[(HYDROXYAMINO)CARBONYL]-4,6-DIMETHYLPHENYL](PHENYLMETHYL)AMINO]SULFONYL]PHENOXY]ETHYL]-2-BENZOFURANCARBOXAMIDE | [CAS]
307002-73-9 | [Synonyms]
WAY 170523
WAY 170523 >=98% (HPLC)
N-[2-[4-[benzyl-[2-(hydroxycarbamoyl)-4,6-dimethylphenyl]sulfamoyl]phenoxy]ethyl]-1-benzofuran-2-carboxamide
N-[2-[4-[[[2-[(HYDROXYAMINO)CARBONYL]-4,6-DIMETHYLPHENYL](PHENYLMETHYL)AMINO]SULFONYL]PHENOXY]ETHYL]-2-BENZOFURANCARBOXAMIDE
2-Benzofurancarboxamide, N-[2-[4-[[[2-[(hydroxyamino)carbonyl]-4,6-dimethylphenyl](phenylmethyl)amino]sulfonyl]phenoxy]ethyl]- | [Molecular Formula]
C33H31N3O7S | [MDL Number]
MFCD09753279 | [MOL File]
307002-73-9.mol | [Molecular Weight]
613.68 |
| Chemical Properties | Back Directory | [density ]
1.352±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at RT | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
8.50±0.42(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
WAY 170523 is a matrix metalloproteinase inhibitor. | [Definition]
ChEBI: N-[2-[4-[[2-[(hydroxyamino)-oxomethyl]-4,6-dimethylphenyl]-(phenylmethyl)sulfamoyl]phenoxy]ethyl]-2-benzofurancarboxamide is a sulfonamide. | [Biological Activity]
Potent and selective inhibitor of MMP-13 (IC 50 values are 17, 945, > 1000 and > 10000 nM for MMP-13, MMP-9, TACE and MMP-1 respectively). | [IC 50]
MMP13: 17 nM (IC50); MMP-9: 945 nM (IC50); MMP-1: 10 μM (IC50) | [storage]
Desiccate at RT |
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