| Identification | Back Directory | [Name]
FARGESIN | [CAS]
31008-19-2 | [Synonyms]
FARGESIN
Methyl pluviatilol
(1β,5β)-2α-(3,4-Dimethoxyphenyl)-6β-(1,3-benzodioxole-5-yl)-3,7-dioxabicyclo[3.3.0]octane
(1S,3aβ,6aβ)-1β-(1,3-Benzodioxole-5-yl)-4α-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan
5-[(1β,3aβ,4α,6aβ)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole
(1R)-4β-(1,3-Benzodioxole-5-yl)-3aβ,4,6,6aβ-tetrahydro-1α-(3,4-dimethoxyphenyl)-1H,3H-furo[3,4-c]furan
rel-5-[(1R,3aS,4S,6aS)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole
1,3-Benzodioxole,5-[(1R,3aS,4S,6aS)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-,rel- | [EINECS(EC#)]
202-110-6 | [Molecular Formula]
C21H22O6 | [MDL Number]
MFCD07781423 | [MOL File]
31008-19-2.mol | [Molecular Weight]
370.4 |
| Chemical Properties | Back Directory | [Melting point ]
132.0 to 136.0 °C | [Boiling point ]
506.4±50.0 °C(Predicted) | [density ]
1.265±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Soluble in chloroform, ethanol and methan | [form ]
powder to crystal | [color ]
White to Light yellow |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the flower buds of Magnolia officinalis and Magnolia grandiflora. | [Uses]
Fargesin is a bioactive neolignan isolated from magnolia plants, which is widely used in the treatment of managing rhinitis, inflammation, histamine, sinusitis, and headache. Also, it is potential antagonist which could protect against myocardial ischemia/reperfusion injury in rats. | [in vivo]
Fargesin has antihypertensive effect in 2K1C hypertensive rats via inhibiting oxidative stress and promoting NO release[1].
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