| Identification | More | [Name]
L-3,5-DIFLUOROPHE | [CAS]
31105-91-6 | [Synonyms]
3,5-DIFLUORO-L-PHENYLALANINE
H-PHE(3,5-DIF)-OH
H-PHE(3,5-F2)-OH
H-PHE(M-F2)-OH
L-3,5-DIFLUOROPHE
L-(3,5-DIFLUORO-PHENYL)ALANINE
(S)-2-AMINO-3-(3,5-DIFLUORO-PHENYL)-PROPIONIC ACID
1(S)-2-AMINO-3-(3,5-DIFLUOROPHENYL)PROPANOIC ACID
3-(3,5-DIFLUOROPHENYL)-L-ALANINE
L-3,5-Difluoro-phe-OH | [EINECS(EC#)]
200-528-9 | [Molecular Formula]
C9H9F2NO2 | [MDL Number]
MFCD01631987 | [Molecular Weight]
201.17 | [MOL File]
31105-91-6.mol |
| Chemical Properties | Back Directory | [Boiling point ]
295.1±40.0 °C(Predicted) | [density ]
1.379±0.06 g/cm3(Predicted) | [storage temp. ]
Store at 0-5°C | [solubility ]
Methanol (Slightly), Water (Slightly) | [form ]
Solid | [pka]
2.13±0.20(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C9H9F2NO2/c10-6-1-5(2-7(11)4-6)3-8(12)9(13)14/h1-2,4,8H,3,12H2,(H,13,14)/t8-/m0/s1 | [InChIKey]
QFGMPXZFCIHYIR-QMMMGPOBSA-N | [SMILES]
C(O)(=O)[C@H](CC1=CC(F)=CC(F)=C1)N | [CAS DataBase Reference]
31105-91-6(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Cream colored powder | [Uses]
H-Phe(3,5-DiF)-OH is a difluorophenylalanines in the L-configuration [L-(F2)Phe]. H-Phe(3,5-DiF)-OH can be incorporated into the thrombin receptor-tethered ligand peptide SFLLRNP to identify the phenyl hydrogens of the Phe-2 residue involved in the CH/π receptor interaction[1]. | [References]
[1] Fujita T, et al. Synthesis of a complete set of l-difluorophenylalanines, l-(F2)Phe, as molecular explorers for the CH/π interaction between peptide ligand and receptor. Tetrahedron Letters. 2000, 41(6):923-927. |
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