| Identification | Back Directory | [Name]
10H-Phenothiazine-10-propanamine,2-chloro-N,N-dimethyl-, 5-oxide, hydrochloride (1:1) | [CAS]
316-07-4 | [Synonyms]
Chlorpromazine-001-HCl
Opromazine hydrochloride
Chlorpromazine Impurity 1 HCl
10H-Phenothiazine-10-propanamine,2-chloro-N,N-dimethyl-, 5-oxide, hydrochloride (1:1) | [Molecular Formula]
C17H19ClN2OS.ClH | [MDL Number]
MFCD00798915 | [MOL File]
316-07-4.mol | [Molecular Weight]
371.32 |
| Hazard Information | Back Directory | [Uses]
Opromazine hydrochloride is an antipsychotic medication that exhibits sedative and antiemetic pharmacological effects, making it effective for treating psychiatric disorders such as schizophrenia and psychosis. Opromazine hydrochloride functions by reducing dopaminergic activity through the blockade of dopamine receptors in the brain. Opromazine hydrochloride has been analyzed for its metabolites in various microsomal enzymes, revealing differences in formation rates that underscore the variability of drug-metabolizing enzymes in human liver and placenta microsomes. | [References]
[1] Establishment of LC-MS/MS method for quantifying chlorpromazine metabolites with application to its metabolism in liver and placenta microsomes DOI:10.1016/j.jpba.2023.115457 |
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