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317331-86-5

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317331-86-5 Structure

317331-86-5 Structure
IdentificationBack Directory
[Name]

N-Succinimidyl-5-(2-pyridyldithio)valerate
[CAS]

317331-86-5
[Synonyms]

SPDV
N-Succinimidyl-5-(2-pyridyldithio)valerate
Pentanoic acid, 5-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
[Molecular Formula]

C14H16N2O4S2
[MDL Number]

MFCD26522028
[MOL File]

317331-86-5.mol
[Molecular Weight]

340.42
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
[InChI]

InChI=1S/C14H16N2O4S2/c17-12-7-8-13(18)16(12)20-14(19)6-2-4-10-21-22-11-5-1-3-9-15-11/h1,3,5,9H,2,4,6-8,10H2
[InChIKey]

ABQGFYSYSCHJNB-UHFFFAOYSA-N
[SMILES]

C(ON1C(=O)CCC1=O)(=O)CCCCSSC1=NC=CC=C1
Hazard InformationBack Directory
[Uses]

SPDV is a cleavable ADC linker used for diagnosis and treatment of cancer or B cell proliferative diseas.
[IC 50]

Disulfide Cleavable Linker; Cleavable Linker
[References]

[1] Allen J. Ebens, et al. Antibodies and immunoconjugates and uses therefor. WO2007140371A2.
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