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890409-85-5

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890409-85-5 Structure

890409-85-5 Structure
IdentificationBack Directory
[Name]

Py-ds-dMBut-OSu
[CAS]

890409-85-5
[Synonyms]

SPDMV
Py-ds-dMBut-OSu
2,5-dioxopyrrolidin-1-yl 4-methyl-4-(pyridin-2-yldisulfanyl)pentanoate
2,5-dioxopyrrolidin-1-yl 4-methyl-4-(pyridin-2-yldisulfaneyl)pentanoate
4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid N-Hydroxy succinimide ester
Pentanoic acid, 4-methyl-4-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
[Molecular Formula]

C15H18N2O4S2
[MDL Number]

MFCD20230415
[MOL File]

890409-85-5.mol
[Molecular Weight]

354.44
Chemical PropertiesBack Directory
[Boiling point ]

487.8±55.0 °C(Predicted)
[density ]

1.36±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

1.91±0.19(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs)[1].
[IC 50]

Disulfide Cleavable Linker
[References]

[1] Daniel Teufel, et al. Bicyclic peptide-toxin conjugates specific for mt1-mmp. WO2017191460A1.
Spectrum DetailBack Directory
[Spectrum Detail]

Py-ds-dMBut-OSu(890409-85-5)1HNMR
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