| Identification | Back Directory | [Name]
2-OXOADIPIC ACID, 98 | [CAS]
3184-35-8 | [Synonyms]
2-Oxoadipate
Oxoadipic acid
2-oxoadipic acid
2-Ketoadipic acid
A-KETOADIPIC ACID
alpha-Oxoadipic acid
2-OXOADIPIC ACID, 98
alpha-ketoadipicacid
2-oxohexanedioic acid
Hexanedioic acid, 2-oxo-
2-Oxoadipic acid >=95.0% (HPLC) | [Molecular Formula]
C6H8O5 | [MDL Number]
MFCD00010004 | [MOL File]
3184-35-8.mol | [Molecular Weight]
160.12 |
| Chemical Properties | Back Directory | [Melting point ]
123-125 °C(lit.) | [Boiling point ]
364.3±25.0 °C(Predicted) | [density ]
1.405±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Water: 250 mg/ml, sonicated | [form ]
A solid | [pka]
2.53±0.54(Predicted) | [color ]
Off-white to light yellow | [InChI]
1S/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11) | [InChIKey]
FGSBNBBHOZHUBO-UHFFFAOYSA-N | [SMILES]
OC(=O)CCCC(=O)C(O)=O | [LogP]
-1.220 (est) |
| Hazard Information | Back Directory | [Uses]
Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine. | [Definition]
ChEBI: 2-oxoadipic acid is an oxo dicarboxylic acid that is adipic acid substituted by an oxo group at position 2. It has a role as a mouse metabolite and a human urinary metabolite. It is functionally related to an adipic acid. It is a conjugate acid of a 2-oxoadipate(2-). | [Synthesis Reference(s)]
Tetrahedron, 51, p. 1867, 1995 DOI: 10.1016/0040-4020(94)01054-4 | [Biochem/physiol Actions]
Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metabolite transporters. | [IC 50]
Human Endogenous Metabolite | [References]
[1] Shibata K, et al. Fluorometric determination of 2-oxoadipic acid, a common metabolite of tryptophan and lysine, by high-performance liquid chromatography with pre-chemical derivatization. Biosci Biotechnol Biochem. 2011;75(1):185-7. Epub 2011 Jan 7. DOI:10.1271/bbb.100723 |
|
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Henan Alpha Chemical Co., Ltd.
|
| Telephone: |
0371-55055611 18137792234 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList31206/0.htm |
| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
|
| Telephone: |
+86-029-81138252 +86-173 9270 1263 |
| Website: |
https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-222/ |
| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
cjbscvictory
|
| Telephone: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
|