| Identification | Back Directory | [Name]
ACETYL-ADHESIN (1025-1044) AMIDE | [CAS]
320350-56-9 | [Synonyms]
P1025
AC-ADHESIN (1025-1044) AMIDE
ACETYL-ADHESIN (1025-1044) AMIDE
N-Acetyl-Adhesin (1025-1044) amide
N-ACETYL-ADHESIN AMIDE FRAGMENT 1025-1044
AC-GLN-LEU-LYS-THR-ALA-ASP-LEU-PRO-ALA-GLY-ARG-ASP-GLU-THR-THR-SER-PHE-VAL-LEU-VAL-NH2
ACETYL-GLN-LEU-LYS-THR-ALA-ASP-LEU-PRO-ALA-GLY-ARG-ASP-GLU-THR-THR-SER-PHE-VAL-LEU-VAL-NH2
L-Valinamide,N2-acetyl-L-glutaminyl-L-leucyl-L-lysyl-L-threonyl-L-alanyl-L-α-aspartyl-L-leucyl-L-prolyl-L-alanylglycyl-L-arginyl-L-α-aspartyl-L-α-glutamyl-L-threonyl-L-threonyl-L-seryl-L-phenylalanyl-L-valyl-L-leucyl-
L-Valinamide, N2-acetyl-L-glutaminyl-L-leucyl-L-lysyl-L-threonyl-L-alanyl-L-α-aspartyl-L-leucyl-L-prolyl-L-alanylglycyl-L-arginyl-L-α-aspartyl-L-α-glutamyl-L-threonyl-L-threonyl-L-seryl-L-phenylalanyl-L-valyl-L-leucyl- (9CI) | [Molecular Formula]
C97H160N26O32 | [MDL Number]
MFCD02262418 | [MOL File]
320350-56-9.mol | [Molecular Weight]
2202.46 |
| Hazard Information | Back Directory | [Uses]
Acetyl-Adhesin (1025-1044) amide is a 20-peptide fragment of Streptococcus pyogenes cell surface adhesin that acts as an antimicrobial peptide to specifically inhibit the binding of adhesin to salivary receptors and prevent recolonization of Streptococcus pyogenes[1]. | [Biological Activity]
Antimicrobial peptide th at has been shown to specifically inhibit binding of a cell surface adhesion of Streptococcus mutans, the main etiological agent of dental caries, to salivary receptors in vitro. | [References]
[1] C G Kelly, et al. ?A synthetic peptide adhesion epitope as a novel antimicrobial agent. Nat Biotechnol. 1999 Jan;17(1):42-7. DOI:10.1038/5213 |
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