ChemicalBook--->CAS DataBase List--->321839-75-2

321839-75-2

321839-75-2 Structure

321839-75-2 Structure
IdentificationBack Directory
[Name]

SSR 125543A
[CAS]

321839-75-2
[Synonyms]

SSR 125543A
Crinecerfont
SSR-125543 hydrochloride
Crinecerfont hydrochloride
[Molecular Formula]

C27H29Cl2FN2OS
[MDL Number]

MFCD05260970
[MOL File]

321839-75-2.mol
[Molecular Weight]

519.5
Chemical PropertiesBack Directory
[storage temp. ]

4°C, away from moisture and light
[solubility ]

DMSO: 2 mg/mL, clear
[form ]

Solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

Crinecerfont (SSR-125543) hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research[1]. Crinecerfont (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
[References]

[1] Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia (CAHtalyst).
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