| Identification | Back Directory | [Name]
Fraxamoside | [CAS]
326594-34-7 | [Synonyms]
Fraxamoside
2H-Pyran-4-acetic acid, 2-[[6-O-[(1R)-1-(3,4-dihydroxyphenyl)-2-hydroxyethyl]-β-D-glucopyranosyl]oxy]-3-ethylidene-3,4-dihydro-5-(methoxycarbonyl)-, intramol. 4,2''-ester, (2S,3E,4S)- | [Molecular Formula]
C25H30O13 | [MDL Number]
MFCD20261047 | [MOL File]
326594-34-7.mol | [Molecular Weight]
538.5 |
| Chemical Properties | Back Directory | [Boiling point ]
825.8±65.0 °C(Predicted) | [density ]
1.468±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
9.44±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Fraxamoside shows significant free radical scavenging effect against DPPH(EC50=66 uM).
Fraxamoside is a xanthine oxidase inhibitor (XOI) comparable in potency in vitro to the standard antigout drug allopurinol. | [Uses]
Fraxamoside is a competitive xanthine oxidase inhibitor with an IC50 of 16.1 μM and a Ki of 0.9 μM[1]. | [References]
[1] Vitale RM, et al. Structure-activity relationships of fraxamoside as an unusual xanthine oxidase inhibitor. J Enzyme Inhib Med Chem. 2017 Dec;32(1):345-354. DOI:10.1080/14756366.2016.1252758 |
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