| Identification | Back Directory | [Name]
CHLOROGENTISYL ALCOHOL | [CAS]
32744-80-2 | [Synonyms]
AMUDOL
CHLOROGENTISYL ALCOHOL
3-Chlorogentisyl alcohol
3-Chloro-2,5-dihydroxybenzyl alcohol
2,5-Dihydroxy-3-chlorobenzyl alcohol
2-(Hydroxymethyl)-6-chlorohydroquinone
2-Chloro-6-(hydroxymethyl)-1,4-benzenediol
1,4-Benzenediol, 2-chloro-6-(hydroxymethyl)- | [Molecular Formula]
C7H7ClO3 | [MDL Number]
MFCD08274565 | [MOL File]
32744-80-2.mol | [Molecular Weight]
174.58 |
| Chemical Properties | Back Directory | [solubility ]
DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/mlPBS (pH 7.2): Sparingly Soluble: 1-10 mg/ml | [form ]
Solid | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
3-Chlorogentisyl alcohol is a potent E. coli β-glucuronidase inhibitor with an IC50 value of 0.74 μM, an Ki value of 0.58 μM. 3-Chlorogentisyl alcohol shows antiproliferative activity. 3-Chlorogentisyl alcohol has the potential for the research of anti-cancer and anti-inflammatory therapies[1]. | [References]
[1] YichaoGe， et al. Exploring gabosine and chlorogentisyl alcohol derivatives from a marine-derived fungus as EcGUS inhibitors with informatic assisted approaches. European Journal of Medicinal Chemistry, 2022, 114699. |
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