| Identification | Back Directory | [Name]
lasiodiplodin | [CAS]
32885-81-7 | [Synonyms]
lasiodiplodin
(S)-Lasiodiplodin
(3S)-Lasiodiplodin
(S)-3,4,5,6,7,8,9,10-Octahydro-12-hydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclododecin-1-one | [EINECS(EC#)]
628-471-3 | [Molecular Formula]
C17H24O4 | [MOL File]
32885-81-7.mol | [Molecular Weight]
292.37 |
| Chemical Properties | Back Directory | [Melting point ]
183-186 °C | [Boiling point ]
500.4±50.0 °C(Predicted) | [density ]
1.072±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
8.23±0.40(Predicted) |
| Hazard Information | Back Directory | [Description]
Lasiodiplodin inhibits electron transport chain.
Lasiodiplodin shows moderate suppression effects on induced NO production, suggest that it may have potential anti-inflammatory activity. | [Uses]
Lasiodiplodin is a potent anti-leukemic macrolide can be isolated from Euphorbia splendens[1]. | [target]
ATPase | NO | TNF-α | [References]
[1] Leet K H, et al. Lasiodiplodin, a potent antileukemic macrolide from Euphorbia splendens[J]. Phytochemistry, 1982, 21(5): 1119-1121. |
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