| Identification | Back Directory | [Name]
WITHANOLIDE A(P) | [CAS]
32911-62-9 | [Synonyms]
Withaniol
WITHANOLIDE A(P)
WITHANOLIDE A(SH)
Withanolide A (15 mg)
Withanolide A 32911-62-9
5,20alpha-Dihydroxy-6alpha,7alpha-epoxy-1-oxowitha-2,24-dienolide
(20R,22R)-5α,20-Dihydroxy-6α,7α:22,26-diepoxyergosta-2,24-diene-1,26-dione
(22R)-6α,7α-Epoxy-5,20,22-trihydroxy-1-oxo-5α-ergosta-2,24-dien-26-oic acid δ-lactone
(22R)-1-Oxo-5,20,22-trihydroxy-6α,7α-epoxy-5α-ergosta-2,24-diene-26-oic acid δ-lactone
(5α,6α,7α,22R)-6,7-Epoxy-5,20,22-trihydroxy-1-oxo-ergosta-2,24-dien-26-oic acid δ-lactone
Ergosta-2,24-dien-26-oic acid, 6,7-epoxy-5,20,22-trihydroxy-1-oxo-, δ-lactone, (5α,6α,7α,22R)- | [EINECS(EC#)]
628-471-3 | [Molecular Formula]
C28H38O6 | [MDL Number]
MFCD07779143 | [MOL File]
32911-62-9.mol | [Molecular Weight]
470.6 |
| Chemical Properties | Back Directory | [Melting point ]
305℃ (DEC.) | [Boiling point ]
651.6±55.0 °C(Predicted) | [density ]
1.264 | [storage temp. ]
-20°C | [solubility ]
methanol: soluble1mg/mL, clear, colorless | [form ]
powder | [pka]
13.05±0.70(Predicted) | [color ]
white | [Major Application]
food and beverages | [InChIKey]
DXWHOKCXBGLTMQ-OCNHUHSRNA-N | [SMILES]
CC1=C(C)C(=O)O[C@H](C1)[C@](C)(O)[C@H]2CC[C@H]3[C@H]4[C@H](CC[C@]23C)[C@@]5(C)C(=O)C=CC[C@]5(O)[C@H]6O[C@@H]46 |
| Hazard Information | Back Directory | [Uses]
Withanolide A, is a neuritogenic steroid. It may act as deterrent for feeding insect larva and other herbivores. Withaferin A, causes activation of Notch2 and Notch4 in human breast cancer cells, and thus used as novel anticancer agents. | [Definition]
ChEBI: Withanolide A is a withanolide. | [Biological Activity]
C28-steroidal lactone th at can induce nerve development and improve nervous system function. Potential therapeutic for neurologic disorders like Alzheimer′s and Parkinson′s disease. In primary r at cortical neuronswithanolide A significantly up-regulated IDE levelsa prominent enzyme involved in degrading amyloid β proteinwhich may help to clear excess amyloid β protein from an Alzheimerμs-inflicted brain. |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Nanjing LuoDa Chemical Co., Ltd
|
| Telephone: |
025-66016961 13382082786; |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList20138/0_EN.htm |
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