| Identification | Back Directory | [Name]
4-Chloro-2-(methylthio)pyrimidine-5-carbonitrile ,97% | [CAS]
33089-15-5 | [Synonyms]
4-Chloro-2-methylthio-5-cyanopyrimidine
4-Chloro-2-(methylthio)pyrimidine-5-carbonitrile
4-chloro-2-(methylthio)-5-pyrimidinecarbonitrile
5-Pyrimidinecarbonitrile, 4-chloro-2-(methylthio)-
4-Chloro-2-methylsulfanyl-pyrimidine-5-carbonitrile
4-Chloro-2-(methylthio)pyrimidine-5- carbonitrile 97%
4-Chloro-2-(methylsulphanyl)pyrimidine-5-carbonitrile
4-Chloro-2-(methylthio)pyrimidine-5-carbonitrile ,97%
4-Chloro--2-methylsulfanyl-pyrimididine-5-carbonitrile
4-Chloro-2-(methylthio)pyrimidine-5-carbonitrile ,97% ISO 9001：2015 REACH | [EINECS(EC#)]
813-495-0 | [Molecular Formula]
C6H4ClN3S | [MDL Number]
MFCD00507261 | [MOL File]
33089-15-5.mol | [Molecular Weight]
185.63 |
| Chemical Properties | Back Directory | [Melting point ]
67-68 °C(Solv: benzene (71-43-2); ligroine (8032-32-4)) | [Boiling point ]
340.7±22.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [form ]
crystals | [pka]
-3.26±0.29(Predicted) | [color ]
Off-white | [InChI]
InChI=1S/C6H4ClN3S/c1-11-6-9-3-4(2-8)5(7)10-6/h3H,1H3 | [InChIKey]
IGIRTCCCRNZFSQ-UHFFFAOYSA-N | [SMILES]
C1(SC)=NC=C(C#N)C(Cl)=N1 |
| Questions And Answer | Back Directory | [Uses]
4-Chloro-2-methylthiopyrimidine-5-onitrile is an organic intermediate. Literature reports that 4-chloro-2-methylthiopyrimidine-5-onitrile can be used to prepare steroidal anti-androgen compounds, and pharmacological experiments have demonstrated that these compounds possess good anti-prostate cancer activity. |
| Hazard Information | Back Directory | [Chemical Properties]
White solid | [Synthesis]
Dissolve 2 g (6.6 mmol) of ethyl 4-chloro-2-methylthiopyrimidine-5-carboxylate of raw material in 10 ml of anhydrous ethanol, add 0.68 g of NaOH solid, 10 ml of water, and raise the temperature to .
reflux. after 1h TLC showed complete reaction. Spin dry |
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