| Hazard Information | Back Directory | [Description]
T-226296 is a melanin concentrating hormone receptor 1 (MCHR1) antagonist. | [Uses]
T-226296 is an oral active and selective melanin-concentrating hormone receptor antagonist with the IC50 values of 5.5 nM and 8.6 nM for human SLC-1 and rat SLC-1, respectively. T-226296 can be used for study of obesity and insulin resistance[1]. | [References]
[1] Takekawa S, et al. T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist. Eur J Pharmacol. 2002;438(3):129-135. DOI:10.1016/s0014-2999(02)01314-6 |
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