ChemicalBook--->CAS DataBase List--->33483-65-7

33483-65-7

33483-65-7 Structure

33483-65-7 Structure
IdentificationMore
[Name]

trans-4-Methylcyclohexylamine hydrochloride
[CAS]

33483-65-7
[Synonyms]

TRANS-4-METHYL-CYCLOHEXYLAMINE HCL
TRANS-4-METHYLCYCLOHEXYLAMINE HYDROCHLORIDE
[Molecular Formula]

C7H16ClN
[MDL Number]

MFCD07368256
[Molecular Weight]

149.66
[MOL File]

33483-65-7.mol
Chemical PropertiesBack Directory
[Melting point ]

260 °C
[storage temp. ]

Sealed in dry,Room Temperature
[Appearance]

White to off-white Solid
[InChI]

InChI=1/C7H15N.ClH/c1-6-2-4-7(8)5-3-6;/h6-7H,2-5,8H2,1H3;1H/t6-,7-;
[InChIKey]

GIRKJSRZELQHDX-MEZFUOHNNA-N
[SMILES]

N[C@@H]1CC[C@@H](C)CC1.[H]Cl |&1:1,4,r|
[CAS DataBase Reference]

33483-65-7(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Safety Statements ]

24/25
[RIDADR ]

UN3259
[HazardClass ]

8
[HS Code ]

29213000
Hazard InformationBack Directory
[Chemical Properties]

Off-white flakes
[Uses]

trans-4-Methylcyclohexylamine hydrochloride is used as glimepiride intermediate.
[Synthesis]

trans-4-Methylcyclohexylamine hydrochloride can be produced by the following steps: a) subjecting a Schiff's base to isomerization by treating thereof with a strong base in a solvent being selected from the group consisting of aliphatic ethers, cyclic ethers, dialkylsulfoxides, or dialkyl sulfones to obtain an isomeric compound; b) subjecting the isomeric compound to acid hydrolysis by treating thereof with a mineral acid to obtain a corresponding salt of trans-4-methylcyclohexylamine; c) optionally converting the obtained trans-4-Methylcyclohexylamine hydrochloride.
Spectrum DetailBack Directory
[Spectrum Detail]

trans-4-Methylcyclohexylamine hydrochloride(33483-65-7)MS
trans-4-Methylcyclohexylamine hydrochloride(33483-65-7)1HNMR
trans-4-Methylcyclohexylamine hydrochloride(33483-65-7)13CNMR
trans-4-Methylcyclohexylamine hydrochloride(33483-65-7)IR1
trans-4-Methylcyclohexylamine hydrochloride(33483-65-7)IR2
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