ChemicalBook--->CAS DataBase List--->334969-03-8

334969-03-8

Request For Quotation

Directory

Identification

334969-03-8 Structure

Identification	Back Directory
[Name] 4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
[CAS] 334969-03-8
[Synonyms] ON01210 Recilisib Recilisib sodium Recilisib sodium salt Recilisib sodium(ON01210) 4-Chlorobenzyl-4-carboxystyryl sulfone 4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID Benzoic acid, 4-[(1E)-2-[[(4-chlorophenyl)methyl]sulfonyl]ethenyl]-
[Molecular Formula] C16H13ClO4S
[MOL File] 334969-03-8.mol
[Molecular Weight] 336.79

Chemical Properties	Back Directory
[Boiling point ] 607.8±55.0 °C(Predicted)
[density ] 1.423±0.06 g/cm3(Predicted)
[storage temp. ] Store at -20°C
[solubility ] DMSO: 35.71 mg/mL (106.03 mM)
[form ] Solid
[pka] 4.00±0.10(Predicted)
[color ] White to off-white

Hazard Information

Back Directory

[Uses]

Recilisib (ON 01210) is a radioprotectant, which can activate AKT, PI3K activities in cells[1].

[Biological Activity]

Recilisib is a radioprotectant that activates the activity of AKT and PI3K in cells.

[in vivo]

Recilisib Sodium (500 mg/kg) significantly increases the rate of recovery and differentiation of primitive bone marrow myeloid progenitor cells in mice. It in combination with radiation reduces CFU numbers in mice, but the Recilisib Sodium-treated mice consistently retain a capability to form differentiated colonies.

[target]

Akt	PI3K
[IC 50] PI3K
[storage] Store at -20°C
[References] [1] Kang AD, et al. ON01210.Na (Ex-RAD) mitigates radiation damage through activation of the AKT pathway. PLoS One. 2013;8(3):e58355. DOI:10.1371/journal.pone.0058355

Spectrum Detail	Back Directory
[Spectrum Detail] 4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID(334969-03-8)¹HNMR

334969-03-8 suppliers list

Company Name:	DebyeTec.com Inc.
Telephone:	18086626237 18086626237
Website:	https://www.chemicalbook.com/ShowSupplierProductsList16955/0.htm

Company Name:	Shanghai YuanYe Biotechnology Co., Ltd.
Telephone:	18916372613
Website:	www.shyuanye.com

Company Name:	Amadis Chemical Company Limited
Telephone:	571-89925085
Website:	http://www.amadischem.com

Company Name:	Twochem Co.Ltd.
Telephone:	021-58111628 15800915896
Website:	cn.twochem.com

Company Name:	Shanghai Jizhi Biochemical Technology Co. Ltd.
Telephone:	021-4009004166/18616739031 18616739031
Website:	www.acmec-e.com/

Company Name:	Shenzhen Polymeri Biochemical Technology Co., Ltd.
Telephone:	+86-400-002-6226 13028896684;
Website:	https://www.rrkchem.com

Company Name:	ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Telephone:	18818260767
Website:	http://www.chemegen.com

Company Name:	Shanghai hongqu biomedical technology co. LTD
Telephone:	88888888888
Website:	www.chemicalbook.com/ShowSupplierProductsList873228/0_EN.htm

Company Name:	Zhengzhou Alpha Chemical Co. LTD
Telephone:	0371-53732842 13383863444
Website:	www.chemicalbook.com/supplier/23629674/

Company Name:	Chunchuang (Wuhan) Technology Co., Ltd
Telephone:	15727060112
Website:	www.chemicalbook.com/showsupplierproductslist1427518/0_en.htm

Company Name:	Shanghai Xuanlin Pharmaceutical Technology Co., Ltd
Telephone:	13955239259;18901805360
Website:	www.chemicalbook.com/ShowSupplierProductsList845223/0_EN.htm

Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Telephone:	010-60605840
Website:	http://www.jm-bio.com/

Company Name:	Hubei Kele Fine Chemical Co., Ltd
Telephone:	027-59101668 19945030958
Website:	www.kerle.cn

Company Name:	Shanghai Taopu Industrial Co., LTD
Telephone:	15900573766 18018507602
Website:	www.chemicalbook.com/showsupplierproductslist1708279/0_en.htm

Company Name:	Bide Pharmatech Ltd.
Telephone:	400-1647117 13681763483
Website:	https://www.bidepharm.com/

Company Name:	Kaifeng Mingren Pharmaceutical Co.,LTD
Telephone:	0371-65741762
Website:	www.kfmryy.com/

Company Name:	InvivoChem
Telephone:	13549236410
Website:	https://www.invivochem.cn/

Company Name:	TargetMol Chemicals Inc.
Telephone:	4008200310 15002144251
Website:	https://www.targetmol.cn/

Tags:334969-03-8 Related Product Information

922139-31-9 448947-81-7 146986-50-7

334969-03-8

Login

Fast registration