| Identification | Back Directory | [Name]
21-Acetoxy-9-fluoro-11b,17-dihydroxypregna-1,4-diene-3,20-dione | [CAS]
338-98-7 | [Synonyms]
predef
U-6013
biorinil
NSC 12600
NSC 37977
Predef R 2X
21-Acetoxy-9-fluoro-
IsoflupredineAcetate
Isoflupredone acetate
isoflupredone 21-acetate
Isoflupredone Acetate USP
9-fluorprednisoloneacetate
9-fluoroprednisoloneacetate
ISOFLUPREDONE ACETATE (200 MG)
9-Fluoroprednisolone-21-acetate
Isoflupredone Acetate USP/EP/BP
9-alpha-fluoroprednisoloneacetate
21-acetoxy-9-fluoro-11,17-dihydroxy-pregna-1,4-diene-3,20-dione
21-ACETOXY-9-FLUORO-11SS,17-DIHYDROXY-PREGNA-1,4-DIENE-3,20-DIONE
21-Acetoxy-9-fluoro-11,B-17-dihydroxy-pregna-1,4-diene-3,20-dione
21-ACETOXY-9-FLUORO-11BETA,17-DIHYDROXY-PREGNA-1,4-DIENE-3,20-DIONE
21-(Acetyloxy)-9α-fluoro-11β,17α-dihyroxypregna-1,4-diene-3,20-dione
4-diene-3,20-dione,9-fluoro-11-beta,17,21-trihydroxy-pregna-21-acetate
4-diene-3,20-dione,21-(acetyloxy)-9-fluoro-11,17-dihydroxy-pregna-(11-be
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11β)-
9alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11.beta.)-
2-((8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-diMethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate | [EINECS(EC#)]
206-423-9 | [Molecular Formula]
C23H29FO6 | [MDL Number]
MFCD00468096 | [MOL File]
338-98-7.mol | [Molecular Weight]
420.471 |
| Chemical Properties | Back Directory | [Melting point ]
244-246° (dec) | [alpha ]
D23 +108° (c = 0.735 in dioxane) | [Boiling point ]
576.5±50.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Acetone (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Ethanol (Slightly) | [form ]
Solid | [pka]
12.05±0.70(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
Isoflupredone Acetate is an anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.
| [Definition]
ChEBI: 9alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate is a corticosteroid hormone. | [Veterinary Drugs and Treatments]
Isoflupredone acetate is a potent glucocorticoid and like other glucocorticoids
can be used for its antiinflammatory or immunosuppressive
effects. Labeled indications for isoflupredone include: adjunctive
treatment of bovine ketosis, alleviating pain and lameness
associated with musculoskeletal conditions, acute hypersensitivity
reactions, adjunctive treatment of overwhelming infections with
severe toxicity, shock, supportive therapy in the treatment of stress
conditions (e.g., surgery), dystocia, retained placenta, inflammatory
ocular conditions, snakebite and parturient paresis.
In horses, isoflupredone has been used parenterally to reduce
inflammation associated with recurrent airway obstruction (RAO,
“heaves”, COPD).
While the drug could be used in small animals, it is recommended
to use other glucocorticoid agents instead, where there has been
more experience and other approved products for dogs and cats are
available. | [Toxics Screening Level]
The ITSL for Isoflupredone Acetate is 0.01 μg/m3 based on annual averaging. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Labnetwork lnc.
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| Telephone: |
+86-27-50766799 +86-18062016861 |
| Website: |
www.labnetwork.com |
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