| Identification | Back Directory | [Name]
Demethyl tetrandrine | [CAS]
33889-68-8 | [Synonyms]
Thaligine
Menisidine
Nsc 277171
Thalrugosine
Fangchinoline
Hanfangchin B
(R)-Fangchinoline
d-Isofangchinoline
Demethyl tetrandrine
Berbaman-7-ol, 6,6',12-trimethoxy-2,2'-dimethyl-
16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol, 3,4,4a,5,16a,17,18,19-octahydro-12,21,26-trimethoxy-4,17-dimethyl-, (4aS,16aR)- (9CI) | [Molecular Formula]
C37H40N2O6 | [MOL File]
33889-68-8.mol | [Molecular Weight]
608.72 |
| Questions And Answer | Back Directory | [Uses]
Fangchinoline is an isolate from Stephania Tetrandra that shows anti-cancer activity. It inhibits breast adenocarcinoma proliferation through apoptosis induction. In addition, it has been shown to inhibit HIV-Type 1 replication. |
| Chemical Properties | Back Directory | [Melting point ]
212-4°C
(dec. ). | [Boiling point ]
709.7±60.0 °C(Predicted) | [density ]
1.204±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
9.38±0.20(Predicted) | [color ]
Off-White to Pale Beige |
| Hazard Information | Back Directory | [Description]
Thalictrum rugosum Ait also contains this alkaloid which is dextrorotatory with
[o:lbo + 128° (MeOH). The ultraviolet spectrum of this base consists of a single
absorption maximum at 283 flI/J.. | [target]
DNA/RNA Synthesis | [storage]
4°C, protect from light | [References]
Mitscher et al., Chem. Commun., 589 (1971) |
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| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
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