| Identification | More | [Name]
5-(4-CHLOROPHENYL)-2-FURALDEHYDE | [CAS]
34035-03-5 | [Synonyms]
5-(4-CHLOROPHENYL)-2-FURALDEHYDE
5-(4-CHLOROPHENYL)-2-FURANCARBOXALDEHYDE
5-(4-CHLORO-PHENYL)-FURAN-2-CARBALDEHYDE
5-(4-CHLOROPHENYL)FURFURAL
AKOS B004122
AKOS BAR-0548
ART-CHEM-BB B004122
ASISCHEM N16482
AURORA KA-4235
TIMTEC-BB SBB003482
ZERENEX E/4047331
5-(4-Chlorophenyl)-2-furaldehyde, GC 95%
5-(4-Chlorophenyl)furfural, 5-(4-Chlorophenyl)furan-2-carboxaldehyde
5-(4-Chlorophenyl)furfural, 95+% | [Molecular Formula]
C11H7ClO2 | [MDL Number]
MFCD00195947 | [Molecular Weight]
206.63 | [MOL File]
34035-03-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Pale brown needles | [Melting point ]
128-131 °C (lit.) | [Boiling point ]
350.7±32.0 °C(Predicted) | [density ]
1.282±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [form ]
Needles | [color ]
Pale brown | [InChI]
1S/C11H7ClO2/c12-9-3-1-8(2-4-9)11-6-5-10(7-13)14-11/h1-7H | [InChIKey]
ROJGJNINTRCMBL-UHFFFAOYSA-N | [SMILES]
Clc1ccc(cc1)-c2ccc(C=O)o2 | [CAS DataBase Reference]
34035-03-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29321900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Pale brown needles | [Uses]
5-(4-Chlorophenyl)furfural was used as one of the aldehydes in the synthesis of uridine-based library. | [Uses]
5-(4-Chlorophenyl)furfural is a metabolite of Azimilide (A926950, 2 HCl); an oral type III potassium channel blocker agent that blocks both the rapid activating component and the slow activating component of the delayed rectifier potassium current. Both preclinical and clinical studies have demonstrated the efficacy of Azimilide and its safety in the treatment of supraventricular and ventricular tachyarrhythmia. Azimilide is also being studied in a worldwide multicenter trial for prevention of sudden cardiac death in patients after myocardial infarction. | [General Description]
5-(4-Chlorophenyl)furfural is a furfural derivative. | [Synthesis]
The target compounds 5-(4-chlorophenyl)-2-furancarboxaldehyde (1-9) were synthesized using 2-furancarboxaldehyde and 4-chloroaniline as starting materials and the reaction was carried out with reference to the methodology reported in the literature [3,13] and the structures were confirmed by appropriate characterization means. | [References]
[1] Heterocyclic Communications, 2003, vol. 9, # 6, p. 625 - 628
[2] Synthetic Communications, 2005, vol. 35, # 3, p. 333 - 340
[3] Asian Journal of Chemistry, 2013, vol. 25, # 14, p. 7738 - 7742
[4] Asian Journal of Chemistry, 2017, vol. 29, # 4, p. 735 - 741
[5] Russian Journal of Organic Chemistry, 2009, vol. 45, # 9, p. 1375 - 1381 |
|
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|